Can antipsychotic agents cause esophageal dysmotility and orthostatic hypotension in patients with schizophrenia?

Updated: Mar 16, 2018
  • Author: Frances R Frankenburg, MD; Chief Editor: Glen L Xiong, MD  more...
  • Print
Answer

All antipsychotic agents may be associated with esophageal dysmotility, thus increasing the risks of aspiration, choking, and the subsequent risk of pneumonia. Orthostatic hypotension can be problematic at the beginning of therapy, with dose increases, and in elderly patients. This problem is related to alpha1 -blockade and seems to be particularly severe with risperidone and clozapine.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!