What is the role of medical care in the management of schizophrenia?

Updated: Mar 16, 2018
  • Author: Frances R Frankenburg, MD; Chief Editor: Glen L Xiong, MD  more...
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It is important not to neglect the medical care of the person with schizophrenia. Obesity, diabetes, cardiovascular disease, and lung diseases are prevalent in schizophrenia, and the person with schizophrenia often does not receive adequate medical care for such conditions. [77]  A meta-analysis of 16 case-control studies comprising 15 samples (731 patients and 614 controls) found that individuals with first-episode schizophrenia had elevated fasting plasma glucose levels. Additionally, plasma glucose levels after an oral glucose tolerance test, fasting plasma insulin levels, and insulin resistance (homeostatic model assessment of insulin resistance) were all significantly elevated in patients compared with controls. The results demonstrate that altered glucose homeostasis is present from illness onset, showing a direct link between schizophrenia and the development of diabetes. [78]

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