How is schizophrenia differentiated from Wilson disease (hepatolenticular degeneration)?

Updated: Mar 16, 2018
  • Author: Frances R Frankenburg, MD; Chief Editor: Glen L Xiong, MD  more...
  • Print

Wilson disease, also known as hepatolenticular degeneration, is a disorder of the metabolism of copper.

It is an autosomal recessive illness. The first psychiatric symptoms are often vague changes in behavior during adolescence. It is primarily a liver disease.

Laboratory findings include increased urinary levels of copper and low serum levels of copper and ceruloplasmin. Kayser-Fleischer rings (copper deposits around the cornea) can sometimes be seen. The diagnosis is usually confirmed by finding increased hepatic copper at biopsy.

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!