What are the APA recommendations on the evaluation of treatment for panic disorder?

Updated: Mar 21, 2018
  • Author: Mohammed A Memon, MD; Chief Editor: Randon S Welton, MD  more...
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The following are some recommendations from the American Psychiatric Association (APA) [55] :

  • Add or switch to another first-line treatment, if one first-line treatment (e.g., cognitive behavioral therapy [CBT], a selective serotonin reuptake inhibitor [SSRI], a serotonin-norepinephrine reuptake inhibitor [SNRI]) was unsuccessful

  • Augment an antidepressant by adding a benzodiazepine to target residual symptoms

  • Consider alternatives with some empirical support (e.g., monoamine oxidase inhibitors [MAOIs], panic-focused psychodynamic psychotherapy [PFPP]) or less well-supported alternative therapies (monotherapy/augmentation with gabapentin or second-generation antipsychotic or with a psychotherapeutic modality other than CBT or PFPP) when standard treatment strategies have been ineffective or when first- and second-line treatment and augmentation strategies have failed

  • Consult with psychiatrists experienced in treating patients with refractory/resistant panic disorder

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