What are the American Psychiatric Association (APA) recommended interventions for managing opioid dependence and withdrawal?

Updated: Jun 21, 2018
  • Author: David W Dixon, DO; Chief Editor: Glen L Xiong, MD  more...
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The American Psychiatric Association (APA) guidelines identify the following treatment modalities as effective strategies for managing opioid dependence and withdrawal. [6]

  • opioid substitution with methadone or buprenorphine, followed by a gradual taper

  • abrupt opioid discontinuation with the use of clonidine to suppress withdrawal symptoms

  • clonidine-naltrexone detoxification

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