What are the guidelines for the treatment of major depressive disorder (clinical depression) in children and adolescents?

Updated: Aug 06, 2020
  • Author: Jerry L Halverson, MD; Chief Editor: David Bienenfeld, MD  more...
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The Texas Children’s Medication Algorithm Project has created a consensus guideline for the treatment of major depression in pediatric patients that is based on evidence from scientific studies and the clinical expertise of the panel, which included child and adolescent psychiatry clinicians and research experts. [179] The guideline is as follows:

  • For mild depression, CBT or interpersonal psychotherapy (IPT) is recommended first

  • For pharmacologic therapy, SSRIs are the first-line choice

  • If there is no response to the SSRI, switch to a second SSRI

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