What are the APA guidelines for treatment selection for major depressive disorder (clinical depression)?

Updated: Aug 06, 2020
  • Author: Jerry L Halverson, MD; Chief Editor: David Bienenfeld, MD  more...
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In 2011, the American Psychiatric Association (APA) updated its Practice Guideline for the Treatment of Patients with Major Depressive Disorder. [8] The 2011 APA guideline emphasizes the need to customize a treatment plan for each patient based on a careful assessment of symptoms, including rating scale measurements administered by a clinician or the patient, as well as an analysis of therapeutic benefits and side effects.

Treatment should maximize patient function within specific and realistic goals. The initial modality should be chosen on the basis of the following [8] :

  • Clinical assessment

  • Presence of other disorders

  • Stressors

  • Patient preference

  • Reactions to previous treatment

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