Do calcium channel blockers (CCD) impair the effectiveness of antidepressants in the treatment of major depressive disorder (clinical depression)?

Updated: Mar 28, 2019
  • Author: Jerry L Halverson, MD; Chief Editor: David Bienenfeld, MD  more...
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Answer

Case reports have suggested a possible link between calcium channel blockers and depression. The principal concern with these agents, however, is that they may cause resistance to antidepressants.


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