Which disorders should be included in the differential diagnoses of major depressive disorder (clinical depression)?

Updated: Aug 06, 2020
  • Author: Jerry L Halverson, MD; Chief Editor: David Bienenfeld, MD  more...
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The differential diagnosis for depression includes a wide variety of medical disorders, such as the following:

  • Central nervous system diseases (eg, Parkinson disease, dementia, multiple sclerosis, neoplastic lesions)

  • Endocrine disorders (eg, hyperthyroidism, hypothyroidism)

  • Drug-related conditions (eg, cocaine abuse, side effects of some CNS depressants)

  • Infectious disease (eg, mononucleosis)

  • Sleep-related disorders

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