Which treatments are effective for the management of major depressive disorder (clinical depression)?

Updated: Aug 06, 2020
  • Author: Jerry L Halverson, MD; Chief Editor: David Bienenfeld, MD  more...
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Many effective treatments are available for major depressive disorder, including psychotherapy (e.g., cognitive-behavioral therapy, interpersonal psychotherapy, behavior therapy), used either alone or in combination with medication. However, the combined approach provides some patients with the quickest and most sustained response. Uncomplicated depression that is not severe typically responds equally well to psychotherapy or an antidepressant. (See Treatment.)

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