What is the presentation of major depressive disorder (clinical depression)?

Updated: Aug 06, 2020
  • Author: Jerry L Halverson, MD; Chief Editor: David Bienenfeld, MD  more...
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Most patients with major depressive disorder present with a normal appearance. In patients with more severe symptoms, a decline in grooming and hygiene may be observed, as well as a change in weight. Patients may also show the following:

  • Psychomotor retardation

  • Flattening or loss of reactivity in the patient's affect (ie, emotional expression)

  • Psychomotor agitation or restlessness

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