What are the dietary restrictions for patients with bipolar affective disorder (manic-depressive illness)?

Updated: May 30, 2019
  • Author: Stephen Soreff, MD; Chief Editor: Glen L Xiong, MD  more...
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Unless the patient with bipolar disorder, or manic-depressive illness (MDI), is on monoamine oxidase inhibitors (MAOIs), no special diet is required. Patients should be advised not to make significant changes in their salt intake, because increased salt intake may lead to reduced serum lithium levels and reduced efficacy, and reduced intake may lead to increased levels and toxicity.

Although a meta-analysis by Starris et al found strong evidence that bipolar depressive symptoms may be improved by adjunctive use of omega-3, omega-3 does not improve bipolar mania. [112]

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