How does the incidence of bipolar affective disorder (manic-depressive illness) vary by sex?

Updated: May 30, 2019
  • Author: Stephen Soreff, MD; Chief Editor: Glen L Xiong, MD  more...
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BPI occurs equally in both sexes; however, rapid-cycling bipolar disorder (≥4 episodes/y) is more common in women than in men. The incidence of BPII is higher in females than in males. Most studies report a nearly equal male-to-female ratio in the prevalence of bipolar disorder; however, most studies also report an increased risk in women for BPII/hypomania, rapid cycling, and mixed episodes. [63]

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