Which medications are used in the treatment of bipolar affective disorder (manic-depressive illness?)

Updated: May 30, 2019
  • Author: Stephen Soreff, MD; Chief Editor: Glen L Xiong, MD  more...
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Medications used to manage patients with bipolar disorder include the following:

  • Benzodiazepines - for acute agitation (e.g. lorazepam, clonazepam)

  • Antimanic agents (eg, lithium)

  • Anticonvulsants (eg, carbamazepine, valproate sodium, valproic acid, divalproex sodium, lamotrigine)

  • First-generation antipsychotics (eg, inhaled loxapine, haloperidol)

  • Second-generation antipsychotics (eg, asenapine, ziprasidone, quetiapine, risperidone, aripiprazole, olanzapine, olanzapine and fluoxetine, clozapine, paliperidone, lurasidone)

  • Phenothiazine antipsychotics (eg, chlorpromazine)

  • Dopamine agonists (eg, pramipexole)

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