Which agents are considered the drugs of choice in the treatment of anxiety disorders?

Updated: Mar 27, 2019
  • Author: Nita V Bhatt, MD, MPH; Chief Editor: David Bienenfeld, MD  more...
  • Print
Answer

Antidepressant agents are the drugs of choice in the treatment of anxiety disorders, particularly the newer agents that have a safer adverse effect profile and higher ease of use than the older tricyclic antidepressants (TCAs), such as selective serotonin reuptake inhibitors (SSRIs). Antidepressants that are not FDA-approved for the treatment of a given anxiety disorder, such as nefazodone and mirtazapine still may be beneficial. Older antidepressants, such as TCAs and monoamine oxidase inhibitors (MAOIs), also are effective in the treatment of some anxiety disorders.

A Cochrane review of second-generation antipsychotic drugs found that quetiapine and risperidone were effective when combined with antidepressants; however, adverse side effects were also reported. [73]


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!