What are the treatment options for social anxiety disorder (social phobia) after a failure to respond to treatment with SSRIs?

Updated: Mar 27, 2019
  • Author: Nita V Bhatt, MD, MPH; Chief Editor: David Bienenfeld, MD  more...
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Answer

Failing this, patients sometimes respond to high-potency benzodiazepines. Long-term treatment data from clinical studies of clonazepam are limited but support the drug’s efficacy. [65] Beta-blockers, clonidine, and buspirone are usually not helpful for long-term treatment, although a beta-blocker such as atenolol, nadolol, or propranolol may be useful for the circumscribed treatment of situational/performance anxiety on an as-needed basis.

Consider tapering medications slowly after 6-12 months of full response. If symptoms reoccur following taper, restart therapy and continue indefinitely. [65]


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