What functional MRI and PET scanning results suggest obsessive-compulsive disorder (OCD)?

Updated: Mar 27, 2019
  • Author: Nita V Bhatt, MD, MPH; Chief Editor: David Bienenfeld, MD  more...
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Answer

Functional MRI and PET scanning have shown increases in blood flow and metabolic activity in the orbitofrontal cortex, limbic structures, caudate, and thalamus, with a trend toward right-sided predominance, in patients with obsessive-compulsive disorder. In some studies, these areas of overactivity have been shown to normalize following successful treatment with either SSRIs or CBT. [41] These imaging modalities, however, are of value for research, and not indicated for normal workups.


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