Which factors have prognostic significance in glioblastoma multiforme (GBM)?

Updated: Jul 01, 2019
  • Author: Jeffrey N Bruce, MD; Chief Editor: Herbert H Engelhard, III, MD, PhD, FACS, FAANS  more...
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Answer

Although no formal studies have been performed, observations indicate that variables, such as young age, prolonged interval between operations, and extent of the second surgical resection, have prognostic significance. [122]

A study by El Hindy et al found that a common regulatory single-nucleotide polymorphism (-938C>A) is a survival prognosticator and a marker for high-risk in patients with glioblastoma multiforme who undergo gross total resection. [123]


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