Which radiation therapies for glioblastoma multiforme (GBM) are under investigation?

Updated: Jul 01, 2019
  • Author: Jeffrey N Bruce, MD; Chief Editor: Herbert H Engelhard, III, MD, PhD, FACS, FAANS  more...
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Answer

Experimental studies are underway in which focal radiation is delivered directly to tumors through an implanted balloon containing interstitial radiation. MRI and MR spectroscopy can be used to monitor therapy. Clinical outcomes from these studies are not yet available.

Radiosensitizers, such as newer chemotherapeutic agents, [71] targeted molecular agents, [40, 41] and antiangiogenic agents [41] may increase the therapeutic effect of radiotherapy. [72]


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