Which medications are used in the treatment of glioblastoma multiforme (GBM)?

Updated: Jul 01, 2019
  • Author: Jeffrey N Bruce, MD; Chief Editor: Herbert H Engelhard, III, MD, PhD, FACS, FAANS  more...
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Answer

Agents used include the following:

  • Temozolomide

  • Nitrosoureas (eg, carmustine [BCNU])

  • Inhibitors of MGMT (eg, O6-benzylguanine)

  • Cisplatin

  • Bevacizumab (alone or with irinotecan) for recurrent glioma

  • Tyrosine kinase inhibitors (eg, gefitinib, erlotinib)

  • Investigational therapies (eg, gene therapy, peptide and dendritic cell vaccines, synthetic chlorotoxins, radiolabeled drugs and antibodies) [20, 21, 22, 23, 24, 25]


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