How are granular cell tumors (GCTs) treated?

Updated: Dec 29, 2018
  • Author: Vladimir O Osipov, MD; Chief Editor: E Jason Abel, MD  more...
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Answer

Treatment is with surgical resection. With benign granular cell tumors, local surgical excision is curative, if complete resection is achieved; however, recurrence is possible even withclear margins. Wide en bloc excision is recommended for malignant lesions.

Radiation and chemotherapy are not needed for benign lesions and are not effective for malignant lesions. However, case reports describe response to pazopanib in patients with metastatic disease. [4]


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