What is the role of external beam radiation therapy (EBRT) in the treatment of papillary thyroid carcinoma (PTC)?

Updated: Jun 18, 2020
  • Author: Ponnandai S Somasundar, MD, MPH, FACS; Chief Editor: Neetu Radhakrishnan, MD  more...
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In patients with stage T4 disease, external beam radiation therapy (EBRT) may be performed to control local tumor growth in areas such as the neck, lungs, mediastinum, bone, and central nervous system. Radiation therapy may be indicated when a large, unresectable tumor is present and the uptake of radioiodine is limited, or when intractable bone pain exists. The American College of Radiology recommends that EBRT use of EBRT for thyroid cancer be considered on a case-by-case basis, as it has not been tested in well-designed, randomized, controlled trials. [58]

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