What is the role of radioiodine therapy in the treatment of papillary thyroid carcinoma (PTC)?

Updated: Jun 18, 2020
  • Author: Ponnandai S Somasundar, MD, MPH, FACS; Chief Editor: Neetu Radhakrishnan, MD  more...
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Answer

Approximately 4-6 weeks after surgical thyroid removal, patients may have radioiodine therapy to detect and destroy any metastasis and residual tissue in the thyroid. The decision for radioactive iodine depends on the size of the tumors removed, the prognostic features (eg, lymphovascular invasion) and the individual endocrinologist’s level of aggressiveness and interpretation of the literature. Patients with low-risk differentiated papillary thyroid cancer have shown excellent responses to total thyroidectomy without radioiodine remnant ablation. [53]


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