How is encapsulated follicular variant of papillary thyroid carcinoma (EFVPTC) distinguished from conventional papillary thyroid carcinoma (PTC)?

Updated: Jun 18, 2020
  • Author: Ponnandai S Somasundar, MD, MPH, FACS; Chief Editor: Neetu Radhakrishnan, MD  more...
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Answer

The encapsulated follicular variant of papillary thyroid carcinoma (EFVPTC) demonstrates highly indolent behavior. To distinguish this variant from conventional papillary thyroid cancer—and reduce the psychological and clinical consequences associated with the diagnosis of cancer—an international team of thyroid pathologists, and the the American Thyroid Association, have recommended reclassifying EFVPTC as "noninvasive follicular thyroid neoplasm with papillary-like nuclear features" (NIFTP). [46, 2]


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