What are the characteristics of papillary thyroid carcinoma (PTC) on immunohistochemistry?

Updated: Jun 18, 2020
  • Author: Ponnandai S Somasundar, MD, MPH, FACS; Chief Editor: Neetu Radhakrishnan, MD  more...
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Answer

On immunohistochemistry, papillary thyroid carcinoma usually exhibits the following pattern:

  • Carcinoembryonic antigen (CEA) negative
  • Calcitonin negative
  • Thyroglobulin positive
  • Keratin positive

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