How does the histologic variant of papillary thyroid carcinoma (PTC) affect prognosis?

Updated: Jun 18, 2020
  • Author: Ponnandai S Somasundar, MD, MPH, FACS; Chief Editor: Neetu Radhakrishnan, MD  more...
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Answer

A retrospective study of clinicopathological outcomes of 6282 patients with PTC demonstrated significant differences in recurrence and disease-specific patient survival with three histologic variants of PTC. Particularly in patients at least 45 years old, patients with tall-cell PTC had the worse prognosis; those with conventional PTC had an intermediate prognosis, and those with follicular-variant PTC had the best prognosis. [1]


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