What are risk factors for mortality in papillary thyroid carcinoma (PTC)?

Updated: Jun 18, 2020
  • Author: Ponnandai S Somasundar, MD, MPH, FACS; Chief Editor: Neetu Radhakrishnan, MD  more...
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Answer

A study by Yu et al found that papillary thyroid microcarcinomas are generally associated with an excellent prognosis; however, 0.5% of patients may die. Risk factors for overall survival include the following:

  • Age older than 45 years
  • Male sex
  • Minority race
  • Node metastases
  • Extrathyroidal invasion
  • Distant metastases

If two or more risk factors are present, patients should be considered for more aggressive management. [30]


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