What are the goals of drug treatment for renal cell carcinoma (RCC)?

Updated: Feb 19, 2021
  • Author: Kush Sachdeva, MD; Chief Editor: E Jason Abel, MD  more...
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The goals of pharmacotherapy are to induce remission, reduce morbidity, and prevent complications. Selected patients with metastatic disease respond to immunotherapy, but many patients with advanced renal cell disease can be offered only palliative therapy.

Options for chemotherapy and endocrine-based approaches are limited, and no hormonal or chemotherapeutic regimen is accepted as a standard of care. Objective response rates with chemotherapy, either single-agent or combination, are usually lower than 15%. Therefore, various biologic therapies have been evaluated.

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