What are NCCN postoperative guidelines for stage IV renal cell carcinoma (RCC)?

Updated: Feb 19, 2021
  • Author: Kush Sachdeva, MD; Chief Editor: E Jason Abel, MD  more...
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For relapsed or stage IV and surgically unresectable disease, the NCCN recommendations are as follows [19] :

  • History and physical exam every 6-16 w in patients receiving systemic therapy, or more often as clinically indicated

  • Laboratory studies as required for the therapeutic agent the patient is receiving

  • Baseline chest, abdominal, and pelvic CT or MRI, with follow-up imaging every -16 w as clinically indicated

  • Consider CT or MRI of the head, at baseline and as clinically indicated, with annual surveillance scans at the clinician’s discretion

  • Spine MRI as clinically indicated

  • Bone scan as clinically indicated

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