What are NCCN postoperative guidelines for stage II and III renal cell carcinoma (RCC)?

Updated: Feb 19, 2021
  • Author: Kush Sachdeva, MD; Chief Editor: E Jason Abel, MD  more...
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Answer

For stage II or III renal cell carcinoma, the NCCN recommends following radical nephrectomy with a history and physical examination every 3-6 mo for 3 y, then annually for up to 5 y, then as clinically indicated. A comprehensive metabolic panel (and other tests as indicated) is recommended every 6 mo for 2 y, annually up to 5 y, then as clinically indicated.

Chest imaging: Baseline chest CT within 3–6 mo with continued imaging (CT preferred) every 3–6 mo for at least 3 y and then annually up

Imaging studies are as follows:

  • Baseline abdominal CT or MRI scanning should be performed within 3-6 mo; then CT, MRI (preferred), or ultrasound every 3-6 mo for at least 3 y, annually up to 5 y, then as clinically indicated

  • A baseline chest CT should be performed within 3-6 mo postoperatively, with CT (preferred) or chest x-ray every 3- mo for at least 3 y, then annually up to 5 y, then as clinically indicated, based on individual patient characteristics and tumor risk factors

  • Additional imaging (ie, bone scan, brain imaging) as symptoms warrant

  • Pelvic imaging, CT or MRI of the head or MRI of the spine, or bone scanning, is peformed as clinically indicated


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