What are NCCN postoperative guidelines for stage I renal cell carcinoma (RCC)?

Updated: Jun 08, 2020
  • Author: Kush Sachdeva, MD; Chief Editor: E Jason Abel, MD  more...
  • Print
Answer

In patients who have undergone ablative techniques for stage I RCC, the NCCN recommends the following:

  • Complete history and physical examination annually
  • Laboratory tests annually, as clinically indicated
  • Abdominal imaging: Abdominal CT or MRI at 3–6 mo following ablative therapy unless otherwise contraindicated then CT or MRI (preferred), or US annually for 5 y or longer as clinically indicated; if there are imaging or clinical concerns for recurrence, then more frequent imaging, renal mass biopsy, or further treatment may be indicated.
  • Chest imaging: Chest x-ray or CT annually for 5 y for patients who have biopsy-proven low-risk RCC, nondiagnostic biopsies, or no prior biopsy

In patients who have undergone partial or radical nephrectomy for stage pT1a or pT1b RCC, the NCCN recommends the following:

  • Complete history and physical examination annually
  • Laboratory tests annually, as clinically indicated
  • Abdominal imaging: Baseline abdominal CT or MRI (preferred), or US within 3–12 mo of surgery, then annually for 3 y or longer as clinically indicated; a more rigorous imaging schedule or technique modality can be considered in cases with positive margins or adverse pathologic features (eg, sarcomatoid, high-grade [grade 3/4], positive margins)
  • Chest imaging: Chest x-ray or CT annually for at least 5 y, then as clinically indicated. A more rigorous imaging schedule or technique modality can be considered in cases with positive margins or adverse pathologic features [21]

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!