What are the treatment options for renal cell carcinoma (RCC)?

Updated: Feb 19, 2021
  • Author: Kush Sachdeva, MD; Chief Editor: E Jason Abel, MD  more...
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The principal treatment options for renal cell cancer are as follows:

  • Surgery
  • Radiation therapy
  • Immunotherapy
  • Molecular-targeted therapy

Surgical resection remains the only known curative treatment for localized renal cell carcinoma, and it also is used for palliation in metastatic disease. Radiofrequency ablation by an interventional radiologist can be considered as an alternative for small lesions in carefully selected patients who are not candidates for surgery. Targeted therapy and immunomodulatory agents are considered standard of care in patients with metastatic disease. Experimental treatment approaches include vaccines and nonmyeloablative allogeneic peripheral blood stem cell transplantation.

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