Which lab studies are performed in the initial workup of renal cell carcinoma (RCC)?

Updated: May 21, 2019
  • Author: Kush Sachdeva, MD; Chief Editor: E Jason Abel, MD  more...
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Answer

The following are initial laboratory studies in the evaluation of suspected renal cell carcinoma (RCC):

  • Urinalysis (UA) with urine cytology (if central lesion)
  • Urine cytology (if central lesion is present, to evaluate for urothelial carcinoma)
  • Complete blood cell (CBC) count with differential
  • Electrolytes
  • Renal profile
  • Liver function tests (LFTs): Aspartate aminotransferase (AST) and alanine aminotransferase (ALT)
  • Serum calcium
  • Other tests as indicated by the patient’s presenting symptoms.

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