How are the risk groups categorized for metastatic renal cell carcinoma (RCC)?

Updated: Feb 19, 2021
  • Author: Kush Sachdeva, MD; Chief Editor: E Jason Abel, MD  more...
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Answer

Both systems categorize patients into the following 3 risk groups:

  • Favorable risk (no risk factors) - Median survival 20 months (MSKCC/Motzer); 2-year overall survival (2y OS) 75% (IMDC)
  • Intermediate risk (1 or 2 risk factors) - Median survival 10 months; 2y OS 53%
  • Poor/high risk group (3 or more risk factors) - Median survival 4 months; 2y OS 7%

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