What are the prognostic criteria used in the International Metastatic RCC Database Consortium (IMDC) risk model for metastatic renal cell carcinoma (RCC)?

Updated: Feb 19, 2021
  • Author: Kush Sachdeva, MD; Chief Editor: E Jason Abel, MD  more...
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Answer

The International Metastatic RCC Database Consortium (IMDC) risk model, validated and further developed by Heng et al, includes the following prognostic criteria [15] :

  • Time from diagnosis to systemic treatment less than 1 year
  • Karnofsky performance status less than 80%
  • Hemoglobin concentration below LLN
  • Serum calcium (corrected for hypoalbuminemia) above ULN
  • Platelet count above the ULN
  • Neutrophil count above the ULN

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