What is the prognosis of renal cell carcinoma (RCC)?

Updated: Feb 19, 2021
  • Author: Kush Sachdeva, MD; Chief Editor: E Jason Abel, MD  more...
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In the United States, death rates from kidney and renal pelvis cancer decreased by about 1% per year from 2009 to 2018. [5] These cancers currently constitute the twelfth leading cause of cancer death. [10]  The 5-year survival rates initially reported by Robson in 1969 were 66% for stage I renal carcinoma, 64% for stage II, 42% for stage III, and only 11% for stage IV. [12, 13] Except for stage I, these survival statistics have remained essentially unchanged for several decades. Surveillance, Epidemiology, and End Results (SEER) data from 2010–2016 showed 5-year relative survival for localized kidney and renal pelvic cancer as 92.6% for localized disease, 70.4% for regional disease, and 13.0% for distant disease. [10]

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