What is the incidence of renal cell carcinoma (RCC) in the US?

Updated: Feb 19, 2021
  • Author: Kush Sachdeva, MD; Chief Editor: E Jason Abel, MD  more...
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From 1975 to 2008, the incidence of kidney cancer rose fairly steadily in the United States, from 7 to 16 cases per 100,000 population. [10]  The increase appears to have been due in part to increased incidental detection because of the wider use of medical imaging. From 2008 to 2017, the incidence rate increased by about 1% per year. [5]  

Currently, cancers of the kidney and renal pelvis are the sixth most common cancer in US men, accounting for 5% of cases, and the ninth most common in US women, accounting for 3% of cases. The American Cancer Society estimates that in 2021 there will be 76,080 cases (48,780 in males and 27,300 in females) of malignant tumors of the kidney and renal pelvis diagnosed, with 13,780 deaths (8790 in males and 4990 in females). [5] Renal cell carcinoma is expected to account for 80% of this incidence and mortality.

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