What is the incidence of renal cell carcinoma (RCC) in the US?

Updated: May 20, 2019
  • Author: Kush Sachdeva, MD; Chief Editor: E Jason Abel, MD  more...
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From 1975 to 2008, the incidence of kidney cancer rose fairly steadily in the United States, from 7 to 16 cases per 100,000 population. [9]  The increase appears to have been due in part to increased incidental detection because of the wider use of medical imaging. Subsequently, incidence rates appear to have remained stable in both men and women. [1]  

Currently, cancers of the kidney and renal pelvis are the sixth most common cancer in US men, accounting for 5% of cases, and the 10th most common in US women, accounting for 3% of cases. The American Cancer Society estimates that in 2018 there will be 65,340 cases (42,680 in males and 22,660 in females) of malignant tumors of the kidney diagnosed, with 14,970 deaths (10,010 in males and 4960 in females). [1] Renal cell carcinoma is expected to account for 80% of this incidence and mortality.

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