What is the incidence of renal cell carcinoma (RCC) in the US?

Updated: Jun 08, 2020
  • Author: Kush Sachdeva, MD; Chief Editor: E Jason Abel, MD  more...
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From 1975 to 2008, the incidence of kidney cancer rose fairly steadily in the United States, from 7 to 16 cases per 100,000 population. [10]  The increase appears to have been due in part to increased incidental detection because of the wider use of medical imaging. Since 2008, incidence rates have remained stable at approximately 15 to 16 cases per 100,000 population. [5]  

Currently, cancers of the kidney and renal pelvis are the sixth most common cancer in US men, accounting for 5% of cases, and the eighth most common in US women, accounting for 3% of cases. The American Cancer Society estimates that in 2020 there will be 73,750 cases (45,520 in males and 28,230 in females) of malignant tumors of the kidney and renal pelvis diagnosed, with 14,830 deaths (9860 in males and 4970 in females). [5] Renal cell carcinoma is expected to account for 80% of this incidence and mortality.

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