Which NSAIDs increase the risk of renal cell carcinoma (RCC)?

Updated: Feb 19, 2021
  • Author: Kush Sachdeva, MD; Chief Editor: E Jason Abel, MD  more...
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A prospective evaluation by Cho et al concluded that longer duration of use of nonaspirin nonsteroidal anti-inflammatory drugs (NSAIDs) may increase the risk for renal cell cancer. [7] Phenacetin-containing analgesics taken in large amounts may be associated with increased incidence of renal cell carcinoma; this agent is no longer approved for use in the United States.

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