What are the signs and symptoms of renal cell carcinoma (RCC)?

Updated: May 21, 2019
  • Author: Kush Sachdeva, MD; Chief Editor: E Jason Abel, MD  more...
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Answer

Renal cell carcinoma may remain clinically occult for most of its course. Only 10% of patients present with the classic triad of flank pain, hematuria, and flank mass.

Other signs and symptoms include the following:

  • Weight loss

  • Fever

  • Hypertension

  • Hypercalcemia

  • Night sweats

  • Malaise

  • A varicocele, usually left sided, due to obstruction of the testicular vein

See Clinical Presentation for more detail.


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