What are the signs and symptoms of renal cell carcinoma (RCC)?

Updated: Feb 19, 2021
  • Author: Kush Sachdeva, MD; Chief Editor: E Jason Abel, MD  more...
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Renal cell carcinoma may remain clinically occult for most of its course. Only 10% of patients present with the classic triad of flank pain, hematuria, and flank mass.

Other signs and symptoms include the following:

  • Weight loss
  • Fever
  • Hypertension
  • Hypercalcemia
  • Night sweats
  • Malaise
  • A varicocele, usually left sided, due to obstruction of the testicular vein

See Presentation for more detail.

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