What are NCCN screening recommendations for patients at increased risk of rectal cancer?

Updated: Apr 06, 2021
  • Author: Burt Cagir, MD, FACS; Chief Editor: N Joseph Espat, MD, MS, FACS  more...
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The National Comprehensive Cancer Network (NCCN) has released separate guidelines for average-risk and high-risk individuals. [91, 33]  For average individuals, the recommendations are nearly identical to those of the joint American Cancer Society (ACS), US Multi-Society Task Force on Colorectal Cancer, and American College of Radiology. However, in 2021 the NCCN lowered the age for starting screening in average-risk individuals from 50 years to 45 years. [91]

The NCCN guidelines provide screening recommendations for patients at increased risk due to a personal or family history of any of the following [33] :

  • > 10 adenomatous polyps
  • ≥2 hamartomatous polyps
  • ≥5 serrated polyps proximal to the sigmoid

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