What are the ASCO criteria for preoperative therapy of pancreatic cancer?

Updated: Oct 02, 2020
  • Author: Tomislav Dragovich, MD, PhD; Chief Editor: N Joseph Espat, MD, MS, FACS  more...
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Preoperative therapy is recommended for patients who meet any of the following criteria [96] :

  • Radiographic findings are suspicious but not diagnostic for extrapancreatic disease
  • Poor performance status or comorbidities not conducive to major abdominal surgery if it is thought that their status might be reversed after treatment
  • A radiographic interface between the primary tumor and mesenteric vasculaturea radiographic interface that does not meet appropriate criteria for primary resection
  • CA 19-9 level (in absence of jaundice) suggestive of disseminated disease

After preoperative treatment, patients should be restaged before making plans for surgery.

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