What are ACCP recommendations for treatment of clinical stage III non–small cell lung cancer (NSCLC)?

Updated: Jul 15, 2021
  • Author: Winston W Tan, MD, FACP; Chief Editor: Nagla Abdel Karim, MD, PhD  more...
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The updated ACCP guidelines recommendations for treatment of clinical Stage III NSCLC include the following [81] :

  • Combined chemoradiotherapy is preferred over radiotherapy alone in most subsets of patients and concurrent chemoradiotherapy is recommended over sequential chemoradiotherapy

  • Consolidation chemotherapy or targeted therapy following definitive chemoradiation is not recommended

  • Neoadjuvant therapy followed by surgery is neither clearly better nor clearly worse than definitive chemoradiation

  • Postoperative radiotherapy improves local control without improving survival

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