What is the efficacy of gefitinib versus docetaxel as second-line therapy for non–small cell lung cancer (NSCLC)?

Updated: Jun 05, 2020
  • Author: Winston W Tan, MD, FACP; Chief Editor: Nagla Abdel Karim, MD, PhD  more...
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Answer

The INTEREST trial studied gefitinib versus docetaxel in the second-line setting and found no significant difference in survival (7.6 vs 8 mo). Based on these data, gefitinib was removed from the United States market for use in new patients and was only available by a restricted access program.


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