What is the role of consolidation chemotherapy after chemoradiation in the treatment of non–small cell lung cancer (NSCLC)?

Updated: Jun 05, 2020
  • Author: Winston W Tan, MD, FACP; Chief Editor: Nagla Abdel Karim, MD, PhD  more...
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Answer

Consolidation chemotherapy after chemoradiation had initially been shown to be beneficial in phase II studies, with docetaxel after chemoradiation with cisplatin/etoposide showing a median survival of 26 months and a 5-year survival of 29%. In phase III testing, however, this regimen did not show improved survival and it proved to be more toxic, so it is no longer recommended outside a clinical trial setting. [136]


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