What is the staging for metastatic (M) involvement in non–small cell lung cancer (NSCLC)?

Updated: Jul 15, 2021
  • Author: Winston W Tan, MD, FACP; Chief Editor: Nagla Abdel Karim, MD, PhD  more...
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Metastatic (M) involvement is as follows:

  • MX - Distant metastasis cannot be assessed

  • M0 - No distant metastasis

  • M1 - Distant metastasis

  • M1a - Separate tumor nodule(s) in a contralateral lobe; tumor with pleural or pericardial nodules or malignant pleural or pericardial effusion

  • M1b - Single extrathoracic metastasis in a single organ (including involvement of a single nonregional node)

  • M1c - Multiple extrathoracic metastases in one or more organs

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