What are common sites of distant metastasis in non–small cell lung cancer (NSCLC)?

Updated: Jul 15, 2021
  • Author: Winston W Tan, MD, FACP; Chief Editor: Nagla Abdel Karim, MD, PhD  more...
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About one third of patients present with symptoms as a result of distant metastases. The most common sites of distant metastasis from lung cancer are as follows:

  • Bone
  • Liver
  • Adrenal glands and intra-abdominal lymph nodes
  • Brain and spinal cord
  • Lymph nodes and skin

Lung cancer can metastasize to virtually any bone, although the axial skeleton and proximal long bones are most commonly involved.

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