What is the incidence of non–small cell lung cancer (NSCLC) in the US?

Updated: Jun 05, 2020
  • Author: Winston W Tan, MD, FACP; Chief Editor: Nagla Abdel Karim, MD, PhD  more...
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In the United States, lung cancer is the second most common cancer, after prostate cancer in men and breast cancer in women, but the most common cause of cancer deaths. The American Cancer Society projects that 228,820 cancers of the lung and bronchus will be diagnosed in the United States in 2020, with 135,720 deaths. [6]  Approximately 85% of those cases are expected to be NSCLC.

In US men, the incidence of lung cancer has been decreasing since the mid-1980s. In US women, however, the rate has been decreasing only since the mid-2000s. From 2004 to 2013, the incidence of lung cancer decreased by 2% per year in men and by 1% per year in women. [6]

Lung cancer death rates for US women are among the highest in the world. Although in the United States, death rates are higher in men than in women, rates for US men are still lower than rates for men in several other countries. [23] These trends in US death rates parallel trends in smoking prevalence over the past 50 years. [6]

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