When are local therapies indicated in the treatment of Kaposi sarcoma (KS)?

Updated: Apr 11, 2019
  • Author: Jessica Katz, MD, PhD, FACP; Chief Editor: Edwin Choy, MD, PhD  more...
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Answer

Local therapy is best suited for patients who require palliation of locally advanced symptomatic disease (eg, radiation) or for those who have cosmetically unacceptable lesions. This therapy is also well suited for patients with significant comorbidities and disease refractory to systemic modalities. It can provide better cosmesis; control bulky lesions that cause bleeding, pain or, edema; and treat extensive skin disease. Local therapy fails to halt the development of new Kaposi sarcoma lesions.


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