What is the global prevalence of Kaposi sarcoma (KS)?

Updated: Apr 11, 2019
  • Author: Jessica Katz, MD, PhD, FACP; Chief Editor: Edwin Choy, MD, PhD  more...
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Answer

International

Prior to the advent of HIV, Kaposi sarcoma was common in central Africa and prevalent in Mediterranean countries and the Middle East. It rarely occurred elsewhere. In Africa, the annual incidence of Kaposi sarcoma is very high at 37.7 per 100,000 in men and 20.5 per 100,000 in women. In Europe, the highest rates of classic Kaposi sarcoma are in Sicily (Ragusa, 30.1 cases per million in men/5.4 cases per million in women) and Sardinia (24.3 cases per million in men/7.7 cases per million in women).

A meta-analysis of the worldwide epidemiology of Kaposi sarcoma found the following incidence rates (per 100,000 person-years) [70] :

  • General population: 1.53 (95% confidence interval [CI] 0.33-7.08) 
  • HIV-infected persons: 481.54 (95% CI 342.36-677.32) 
  • HIV-infected MSM:1397.11 (95% CI 870.55-2242.18)
  • HIV-infected children: 52.94 (95% CI 39.90-70.20) 
  • Transplant recipients: 68.59 (95% CI 31.39-149.86

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