How is Kaposi sarcoma human herpes virus (KSHV) transmitted?

Updated: Apr 11, 2019
  • Author: Jessica Katz, MD, PhD, FACP; Chief Editor: Edwin Choy, MD, PhD  more...
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Answer

KSHV is now thought to be largely transmitted via saliva. Although associated with sexual risk factors, these may just be a surrogate for close contact. [55] Heterosexual risk factors largely do not play a role here. Transmission by blood or blood products can occur but use of leukopoor stored blood is likely to significant reduce this risk. [56] Transmission of KSHV may occur during solid organ donation, but it does not appear to affect clinical outcome in terms of survival or graft loss. In solid organ transplant recipients, the incidence of Kaposi sarcoma may be higher in those who are seropositive than in those who are seronegative. [57]


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